Diagnosis and evaluation of 38 cases of pelvic congestion syndrome and single center experience in intracavitary treatment / 中国医师杂志

Objective:To evaluate the diagnostic evaluation process and the effectiveness and safety of intracavitary therapy for pelvic congestion syndrome (PCS).Methods:A retrospective analysis was conducted on 38 patients admitted to Beijing Shijitan Hospital affiliated to Capital Medical University from March 2019 to February 2022. Combined with the patient′s symptoms, PCS was diagnosed by color Doppler ultrasound, computed tomography venography (CTV), and venography. The ovarian vein was embolized with controllable spring coil and polydocanol foam sclerosing agent. The patients were followed up 1, 3 and 6 months after operation.Results:The total surgical success rate of 38 patients was 100%, and the incidence of complications was 5.3%(2/38); Spring coils (2.8±0.3)per person; The dosage of hardener was (7.0±2.1)ml/person. The improvement rate of patient symptoms was 97.4%(37/38); After 1, 3, and 6 months of surgery, color Doppler ultrasound was reexamined and no recanalization was observed in the embolized ovarian veins; The diameter of the parauterine vein was (2.8±0.5)mm, which was significantly lower than the preoperative (7.5±1.9)mm ( P<0.05); The Visual Analogue Scale (VAS) score was significantly lower than the preoperative score [(2.12±1.87)points vs (7.58±0.82)points, P<0.001]. Conclusions:Process based assessment is helpful in identifying and diagnosing PCS patients who urgently need treatment; Endovascular treatment based on embolization of ovarian vein with controllable spring coil and foam sclerosing agent is minimally invasive, safe and effective.

Ozonoterapia en pacientes con dolor pélvico crónico / Ozone therapy in patients with chronic pelvic pain

Introducción: La factibilidad y seguridad del empleo de la ozonoterapia se evidencia en los resultados expuestos por varios autores, en enfermedades cuyo síntoma fundamental es el dolor crónico. Objetivo: Determinar la evolución clínica de las pacientes con dolor pélvico crónico, tratadas con ozono asociado al tratamiento médico convencional. Métodos: Estudio descriptivo, observacional, retrospectivo, en el que se determinó la evolución clínica de las pacientes con dolor pélvico crónico tratadas con ozono, asociada al tratamiento médico convencional. La muestra fue de 54 mujeres. Las variables utilizadas fueron: edad, causa del dolor pélvico, tiempo de evolución, puntuación de la escala de dolor antes y después de la aplicación de la ozonoterapia y evaluación del tratamiento. Resultados: Prevalecieron las pacientes con edad de 26-35 años. El 57,4 por ciento tenían entre 2 y 2 años de evolución del dolor. La enfermedad inflamatoria pélvica crónica fue la causa de mayor frecuencia con 42,5 por ciento. Antes de la aplicación de la ozonoterapia la media de puntuación en la escala de dolor fue de 6,31, y disminuyó a 3 después del tratamiento, con una evaluación de bien en el 81,1 por ciento de los casos. Conclusiones: Después de la aplicación de la ozonoterapia asociada al tratamiento médico convencional, se produce mejoría clínica, por lo que puede ser una alternativa de tratamiento(AU)

Introduction: The feasibility and safety of the use of ozone therapy is evidenced in the results presented by several authors, in diseases whose main symptom is chronic pain. Objective: To determine the clinical evolution of patients with chronic pelvic pain treated with ozone associated with conventional medical treatment. Methods: Descriptive, observational, retrospective study, in which the clinical evolution of patients with chronic pelvic pain treated from January 2018 to January 2020, with ozone therapy, associated with conventional medical treatment. The sample was 54 women. The variables used were: age, cause of pelvic pain, time of evolution, score on the pain scale before and after the application of ozone therapy, and evaluation of the treatment. Results: Patients aged 26-35 years prevailed. 57,4 percent had between two and four years of pain evolution. Chronic pelvic inflammatory disease was the most frequent cause with 42,5 percent. Before the application of ozone therapy, the mean score on the pain scale was 6.31, and it decreased to 3 after treatment, with an evaluation of good in 81,1percent of the cases. Conclusions: After the application of ozone therapy associated with conventional medical treatment, there is evident clinical improvement, which is why it constitutes an alternative of treatment(AU)

Tratamento endovascular da síndrome de quebra-nozes: relato de caso / Endovascular treatment of Nutcracker syndrome: case report

A dor pélvica crônica é uma doença debilitante, com impacto na qualidade de vida e custos para os serviços de saúde. A síndrome de quebra-nozes é uma importante causa dessa dor, e se refere a um conjunto de sinais secundários à compressão da veia renal esquerda, mais comumente entre a artéria mesentérica superior e a aorta. Seu tratamento ainda permanece controverso e varia de acordo com a gravidade clínica do paciente. Contudo, a técnica endovascular com implante de stent em veia renal tem obtido excelentes resultados. Relatamos um caso de uma paciente de 59 anos submetida a correção endovascular com stent autoexpansível de nitinol. São apresentados dados clínicos, detalhes do procedimento e resultados do acompanhamento dessa paciente. O sucesso técnico foi obtido e não houve relato de complicações pós-operatórias. Pôde-se observar alívio dos sintomas e melhora nos exames de imagem realizados no acompanhamento de curto prazo

Chronic pelvic pain is a debilitating disease that directly impacts on quality of life and generates costs for health services. Nutcracker Syndrome is an important cause of pelvic pain and consists of a set of signs secondary to compression of the left renal vein, most commonly between the superior mesenteric artery and the aorta. Treatment remains controversial and varies depending on the patient's clinical severity. However, endovascular treatment with renal vein stenting has achieved excellent results. We report the case of a 59 year-old female treated by endovascular repair with a self-expanding nitinol stent. Clinical data, details of the procedure, and follow-up results are presented. Technical success was achieved and there patient reported no postoperative complications. Short-term, there was relief from symptoms and follow-up imaging tests showed improvement

Evaluation of embolization for periuterine varices involving chronic pelvic pain secondary to pelvic congestion syndrome

OBJECTIVES: To evaluate the clinical response and success rate after periuterine varices embolization in patients with chronic pelvic pain secondary to pelvic congestion syndrome and to report the safety of endovascular treatment and its rate of complications. METHODS: Retrospective cohort of patients undergoing endovascular treatment of pelvic congestion syndrome in our department from January 2012 to November 2015. Data were analyzed based on patient background, imaging findings, embolized veins, rate of complications, and clinical response as indicated by the visual analog pain scale. RESULTS: We performed periuterine varices embolization in 22 patients during the study, four of which required a second embolization. Seventeen patients reported a reduction in pelvic pain after the first embolization and three patients reported a reduction in pelvic pain after the second embolization. Minor complications were observed in our patients, such as postural hypotension, postoperative pain, and venous perforation during the procedure, without clinical repercussion. CONCLUSION: Periuterine varices embolization in patients with chronic pelvic pain secondary to pelvic congestion syndrome appears to be an effective and safe technique.

<b>A Case of Pelvic Congestion Syndrome Successfully Managed with Keishibukuryogan</b> / 日本東洋医学雑誌

<p>Pelvic congestion syndrome is a condition in women caused by congestion or varicosity of the intrapelvic vein. We report a case of pelvic congestion syndrome managed with keishibukuryogan. The syndrome was diagnosed based on expansion of the left periuterine and ovarian veins.<br>A 61-year-old female presented to our clinic with left lower abdominal pain. NRS was 9 and Terasawa's oketsu score was 40, indicating marked blood stasis. A CT scan revealed vascular expansion (10 mm) of the left ovarian vein. Transvaginal ultrasonography also revealed vascular expansion (6.0 mm) of the left periuterine vein. Based on these findings, a diagnosis of pelvic congestion syndrome was established. She was treated with keishibukuryogan (7.5 g/day). NRS was improved to 1 and Terasawa's oketsu score was improved to 20. The symptoms were resolved within 6 months, and the medication was discontinued.<br>Three months after discontinuation, she presented to our clinic again with left lower abdominal pain. The medication was resumed and the symptom was improved. After 5 months, a contrast enhanced CT scan showed no change of vascular expansion of the left ovarian vein (from 10 to 9 mm). Keishibukuryogan treatment has now been continued for 10 months.</p>

Síndrome de congestión pélvica como causa de dolor pélvico crónico / Pelvic congestion syndrome as a cause of chronic pelvic pain

El síndrome de Congestión Pélvica (SCP) es una causa reconocida de dolor pélvico crónico, el cual también se asocia a dispareunia y a varices a nivel vulvar. El flujo venoso retrógrado a través de venas pélvicas dilatadas y tortuosas secundarias a incompetencia valvular u obstrucción en las venas ováricas se ha considerado como la causa más probable. Se estima que el 60% de las pacientes con varices pélvicas son sintomáticas. La conexión directa con las venas arcuatas en el miometrio, el flujo de baja velocidad y el incremento del diámetro con la maniobra de Valsalva se asocian con la exacerbación de los síntomas. El tratamiento del SCP es aún controversial, pero la embolización endovenosa bilateral con escleroterapia ha reportado disminuir exitosamente los síntomas en la mayoría de los casos.

Pelvic congestion syndrome is a reported cause of chronic pelvic pain, which is also associated with dyspareunia and vulvar varicosities. Retrograde flow through tortuous and dilated pelvic veins that develop secondary to incompetent valves or obstruction in the ovarian vein is considered the most likely cause. It is estimated that up to 60% of patients with pelvic varicosities are symptomatic. Imaging techniques demonstrate multiple dilated veins surrounding the pelvic organs. Direct connection to the arcuate veins in the myometrium, low velocity flow, and increase in diameter after the Valsalva maneuver all are associated with symptoms. The treatment of pelvic congestion syndrome remains controversial, but bilateral transcatheter embolization with sclerotherapy is reported to successfully improve symptoms in most cases.

Síndrome da congestão venosa pélvica e resultados do tratamento endovascular: série de casos / Pelvic congestion syndrome case series: results of endovascular treatment

A Síndrome da Congestão Venosa Pélvica (SCVP) é uma causa de dor pélvica crônica, que afeta principalmente mulheres multíparas em idade reprodutiva. Para o tratamento desta síndrome, a embolização de varizes pélvicas tem demonstrado excelentes resultados. Relatamos uma série inicial de pacientes submetidas a tratamento com embolização de varizes pélvicas e os respectivos resultados de acompanhamento pós-operatório. São apresentados dados clínicos, detalhes do procedimento e resultados do acompanhamento e de exames de imagem de seis pacientes. Dentre estas pacientes, o sucesso técnico foi de 100% e não houve relato de complicações trans ou pós-operatórias graves. Em todos os casos, pôde-se observar alívio dos sintomas e melhora nos resultados de exames de imagens no acompanhamento de curto prazo. Os resultados nesta pequena série de casos indicam que a embolização é um tratamento seguro e efetivo para a SCVP.

Pelvic Congestion Syndrome (PCS) is a cause of chronic pelvic pain that primarily affects multiparous women of reproductive age. Embolization of pelvic varicose veins offers excellent results for treatment of this syndrome. We describe an initial series of patients treated with embolization of pelvic varicose veins and their respective postoperative follow-up results. We provide clinical data, details of the procedures performed and results of follow-up and imaging exams for six patients. The technical success rate with these patients was 100% and there were no reports of serious intraoperative or postoperative complications. In all cases there was relief from symptoms and improvements in the results of imaging exams during short-term follow-up. The results of this small series of cases indicate that embolization is a safe and effective treatment for PCS.

Tratamento endovascular da Sindrome de Quebra-nozes (Nutcracker) / Endovascular treatment of Nutcracker syndrome

A Síndrome do Quebra-nozes se refere a um conjunto de sinais secundários à compressão da veia renal esquerda, mais comumente entre a artéria mesentérica superior e a aorta, levando ao comprometimento do fluxo para a veia cava. O diagnóstico desta síndrome frequentemente é difícil e, por esta razão, o diagnóstico é demorado, em muitos casos. É relatado, nesta publicação, o caso de uma mulher de 51 anos, tratada com sucesso pela embolização da veia ovariana associada ao implante de stent autoexpansível na veia renal esquerda. São discutidos os aspectos técnicos e as dificuldades do procedimento.

Nutcracker syndrome refers to signs and symptoms secondary to compression of the left renal vein, most commonly between the superior mesenteric artery and the aorta, leading to impaired outflow to the vena cava. Diagnosis of this syndrome is often difficult and as result is late in most cases. We report on the case of a 51-year-old woman successfully treated with embolization of the ovarian vein and insertion of a self expandable stent in the left renal vein. Technical details and pitfalls are discussed.

Arterial Phase Display and Signiifcance of Right Ovarian Vein in the Diagnosis of Pelvic Congestion Syndrome / 中国医学影像学杂志

Purpose To investigate the significance of arterial phase display of right ovarian vein (ROV) for patients with pelvic congestion syndrome (PCS) through multi-slice CT angiography (MSCTA) Materials and Methods Forty-three patients with PCS confirmed clinically who underwent MSCTA were involved in the study. Revascularization was realized via add vessel volume rendering technique and maximum intensity projection (MIP) and the relationships among ROV early development, location of converging vascular, development of LOV and pelvic draining veins were analyzed. Results Out of 43 cases of ROV early development during arterial phase, 21 cases (48.8%) took ROV as draining vein of PCS, among which 17 cases (81.0%) converged into the inferior cava vena. In 19 cases (44.2%), ROV took part in the formation of PCS, all originating from the main right renal vein. Three cases (7.0%) were renal vein-derived PCS, among which two ROV originated from the main right renal vein and one from the branch of the right renal vein. Conclusion According to the imaging features of bilateral ovarian veins and pelvic veins, ROV, as draining veins, is associated with the formation of PCS.

Várices pélvicas y síndrome decongestión pélvica en la mujer / Pelvic varicocele and pelvic congestion syndrome in woman

El síndrome de congestión pélvica es una condición clínica caracterizada por la presencia dedolor pélvico crónico y una semiología particular asociada con la presencia de dilataciónde los vasos venosos pélvicos, con o sin reflujo presente. Para su diagnóstico es necesario el hallazgode várices pélvicas, pero no toda mujer con várices pélvicas tiene el síndrome. El método diagnósticoestándar es la venografía selectiva ovárica, aunque recientemente métodos no invasivos, como el ultrasonido doppler y la resonancia magnética dinámica tienen amplia aplicación clínica. El tratamiento varía desde el manejo médico mediante la supresión ovárica con progestágenos a altasdosis o análogos de la hormona liberadora de gonadotropina, pasando por el manejo quirúrgicolaparoscópico o laparotómico de ligadura de venas ováricas bilaterales, ventrosuspensión uterinae histerectomía con salpingooforectomía; así como tratamientos de intervención radiológica, como la embolización de vasos venosos pélvicos. Este artículo busca revisar la literatura del síndromede congestión pélvica con el objetivo de conocer una enfermedad frecuentemente pasada por altoy las alternativas diagnósticas y terapeúticas para tratar dichas pacientes. Esta revisión se realizópor búsqueda electrónica que incluye Medline, Pubmed, The Cochrane Library (incluyendo the Cochrane Database of systematic Reviews) y EMBASE. Los títulos de búsqueda (MeSH) en inglés y español, incluyendo todos los subtítulos y palabras claves fueron “varicose veins,” “pelvic congestionsíndrome,” “várices pélvicas,” “síndrome de congestiónpélvica.” Fueron incluidos artículos y revisiones de temasentre 1952 y 2008.

Pelvic congestion syndrome is the clinical conditioncharacterized by chronic pelvic pain, with a particular semiology associated with the presenceof pelvic varicose veins, with or withoutreflux. For the development of a pelvic congestion syndrome is necessary the presence of pelvicvaricose veins, but not all women with pelvic varicose veins has a pelvic congestion syndrome.The standard diagnostic method is the selective ovarian venography; although lately notinvasive methods such as Doppler ultrasound and dynamic magnetic resonance imaging havewide clinical application. Medical treatment for handling pelvic congestion syndrome variesfrom ovarian suppression with high doses of Progestagens or analogues of GnRH or invasivesurgical laparoscopic/laparatomic ligation of bilateral ovarian veins, uterine ventrosuspensionand hysterectomy with salpingoooforectomy; as well as embolization of pelvic venous vessels.This article seeks to review the literature ofpelvic congestion syndrome in order to meet a condition often overlooked and diagnostic andtherapeutic alternatives to treat these patients. This review was conducted by electronic search including Medline, Pubmed, The Cochrane Library(including the Cochrane Database of Systematic Reviews) and EMBASE. The subject headings (MeSH) in English and Spanish, including all subheadings and key words were “varicoseveins,” “pelvic congestion syndrome”, “pelvic várices “, “pelvic congestion syndrome”. Articlesand reviews of issues from 1952 and 2008 were included.

Clinical study of laparoscopy in treatment of pelvic congestion syndrome after tubal ligation / 中国医师进修杂志

Objective To observe clinical effects of round ligament ventrosuspension or shortening round ligament operation by laparoscopy on treating pelvic congestion syndrome (PCS) after tubal ligation. Methods Thirty patients with PCS were treated in round ligament ventrosuspension or shortening round ligament operation by laparescopy. Follow-up was started from the third month after operative procedure to find out patients' symptoms ameliorated situations. Results Symptoms of all patients were ameliorated in various degrees after operations. The cure rate of the cases was 73.3%(22/30), and the rate of improvement was 20.0% (6/30), and the rate of inefficiency was 6.7% (2/30), and total effectiveness rate was 93.3% (28/30). Conclusions Laparoscopy is chosen to be a routine and first diagnosis or treatment means. Round ligament ventrosuspension or shortening round ligament operation by laparoscopy is a simple, high effective way of treating PCS after tubal ligation.

Comparison of diagnostic value between transabdominal and transvagine color doppler ultrasonography in pelvic varicosis / 中国基层医药

Objective To study the diagnostic value of transabdominal color doppler ultrasonography (TACDU) and transvagino color doppler ultrasonography (TVCDU) in patients with pelvic varicosis (PV).Methods 60 patients with PV were detected by using TACDU and TVCDU respecticely,and the diagnostic value between the two ways were compared. Operational results was used as standard, and the degree of lesion in patients with PV was evaluated based on the results of surgery. Results The venous inside diameter、venous plexus,venous blood flow velocity in PV group were higher than the normal group(t = 2.214,2.310,2. 340, all P ＜ 0.05); The diagnosis rate 91.6% in TVCDU was significantly higher than80.0% in TACDU (χ2 = 3. 794, P ＞ 0.05); The pelvic venous flow velocity(8. 5 ± 2.5)cm/s in mild degree was higher than that (4.6 ± 2.7) cm/s in severe degree (t = 2.378,P ＜ 0. 05). Conclusion The transabdominal color Doppler ultrasound in the diagnosis of pelvic congestion syndrome had important clinical value, transvaginal sonography was superior to transabdominal ultrasound.

A case of pelvic congestion syndrome diagnosed by venography / 대한산부인과학회지

Pelvic congestion syndrome (PCS), which is said to occur due to ovarian vein incompetence, is a recognized cause of chronic pelvic pain (CPP). It is difficult to diagnose PCS because of a variety of symptoms. In addition, it can be underestimated by Computed Tomographic or Magnetic Resonance Imaging. At this time, gonadal venography remains the definitive imaging modality to evaluate patients with PCS. Medical and surgical approaches are available to treat PCS. More recently, however, transcatheter embolotherapy (TCE) has been shown to be both safe and effective. We have experienced a case of pelvic congestion syndrome that was diagnosed by venography.

A Case of Pelvic Congestion Syndrome Presenting with Chronic Left Flank Pain in an Adolescent Girl

Flank Pain is a leading indicator of renal and upper urinary tract disease or trauma, and rarely results from pelvic congestion syndrome. Although pelvic congestion syndrome occurs commonly in multi-parous women, pelvic congestion syndrome should also be considered as the cause of flank pain in an adolescent girl. We report the first case of pelvic congestion syndrome presenting with chronic left flank pain in an adolescent girl.

Experience in pelvic congestion syndrome treated with TCM based on syndrome differentiation / 中华中医药杂志

Pelvic congestion syndrome plagues women's physical and mental health,the morbidity rate has increased in recent years.Based on TCM differentiation and classifications of syndrome,pathogenesis of pelvic congestion syndrome is divided into‘dampness-blood stasis’and‘deficiency of qi resulting blood stasis’2 types.Our Qushi Huayu Decoction and Yiqi Tongyu Decoction have been clinically proven to relieve pain,improve quality of life of the patients,and achieve better clinical effect.